Feline sarcoma virus in Cats (Felis) | Vetlexicon
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Feline sarcoma virus

ISSN 2398-2950

Contributor(s) :


Synonym(s): Feline sarcoma virus, FeSV

Introduction

Classification

Taxonomy

  • Family: Retrovirus.
  • Type: Gammaretrovirus.

Etymology

  • Retro because the viral RNA is reverse transcribed into DNA (proviral DNA).

Distribution

  • Worldwide.
  • Rare.

Significance

  • Feline sarcoma viruses (FeSVs) are recombinant viruses that arise in cats persistently infected with FeLV.
  • Recombinant viruses arise through FeLV recombining with host cellular genes.
  • If reconstruction leads to the incorporation of a cellular oncogene, tumors or leukemias may develop.
  • FeLV recombinant viruses incorporating cellular oncogenes are incapable of replication without the help of wild-type FeLV.
  • There is no evidence of transmission between cats although experimental transmission has been demonstrated.

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Resting Forms

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Clinical Effects

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Diagnosis

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Further Reading

Publications

Refereed papers

Other sources of information

  • Keller E T, Helfand S C (1994) Clinical management of soft-tissue sarcomas. In: Consultations in feline internal medicine 2.  Ed John R. August. W B Saunders Co., Harcourt Brace Jovanovich, Inc. The Curtis Center, Independence Square West, Philadelphia, PA 19106. pp 3-12.
  • Hardy W D Jr. (1987) Oncogenic viruses of cats: the feline leukemia and sarcoma viruses. In: Diseases of the Cat: Medicine and Surgery Ed Holzworth, J. W B Saunders Co., Harcourt Brace Jovanovich, Inc. The Curtis Center, Independence Square West, Philadelphia, PA 19106. pp 256-258.

Organization(s)

  • Companion Animal Diagnostics, Veterinary Diagnostic Services. Faculty of Veterinary Medicine, University of Glasgow, Bearsden Road, Glasgow, G61 1QH, Scotland. Tel: + 44 141 330 5777; Fax: + 44 141 330 5748; E-mail:  companion@vet.gla.ac.uk .