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Hematology: complete blood count (CBC)
Overview
- Study of blood cells.
- Red cells via:
- Packed cell volume (PCV) Hematology: packed cell volume or hematocrit.
- Red blood cell (RBC) count Hematology: red blood cell count.
- RBC indices MCV Hematology: mean corpuscular volume, MCH Hematology: mean corpuscular hemoglobin, MCHC Hematology: mean corpuscular hemoglobin concentration.
- Reticulocyte count.
- Hemoglobin (Hb) concentration Hematology: hemoglobin concentration.
- Erythrocyte morphology.
- White cells via:
- Leucocyte (WBC) count Hematology: leucocyte (WBC) and morphology.
- Differential WBC Hematology: differential leucocyte count.
- Platelets via:
- Platelet count and morphology.
- Stained blood smear Hematology: complete blood count (CBC).
- Automated and/or manual methods.
Uses
Alone
- Most information can be gained from PCV (need RBC count if send to laboratory, because PCV may be falsely elevated if cells swell in post, ie MCV); WBC and differential WBC count; WBC and RBC morphology; platelet estimate and morphology.
- Anemia: PCV, reticulocyte count (aggregate count important in cats to determine whether regeneration is adequate or not), RBC count and morphology and Hb.
Sampling
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Tests
Availability
- Widely available at commercial laboratories.
- Blood smears can be examined in practice. Some in-hospital analyzers or cell counting methods now available.
Validity
Sensitivity
- Generally moderate to low unless blood parasites are recognized.
Specificity
- Generally moderate to low unless blood parasites are recognized.
Result Data
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Further Reading
Publications
Refereed papers
- Recent references from VetMedResource and PubMed.
Other sources of information
- Cowell R L, Tyler R D & Meinkoth J H (1999) Diagnostic Cytology and Hematology of the Dog and Cat. 2nd edn. Mosby, USA.
- Duncan J R, Prasse K W & Mahaffey E A (1994) Veterinary Laboratory Medicine. Clinical Pathology. 3rd edn. Iowa University Press, USA
- Jain N C (1993) Essentials of Veterinary Haematology. Lea & Febiger, USA.