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Blood biochemistry: aspartate aminotransferase

ISSN 2398-2950

Contributor(s) :


Synonym(s): AST, Serum AST, SAST, Glutamic oxalo-acetic transaminase, GOT, Serum GOT, SGOT

Overview

  • Not organ specific, but highest levels in skeletal muscle, cardiac muscle, liver.

Uses

Alone

  • Skeletal muscle damage.
  • Cardiac ischemia.
  • Liver damage.

Other points

Sampling

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Tests

Methodologies

  • Method and reference interval may vary between laboratories.
  • Enzymatic methods commonly used.

Availability

  • Widely available.

Technique intrinsic limitations

  • Results only significant when interpreted in conjunction with other laboratory tests and clinical findings.

Result Data

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Further Reading

Publications

Refereed papers

Other sources of information

  • Ettinger S J & Feldman E C (2000) Eds. Textbook of Veterinary Internal Medicine. 5th edn. W B Saunders & Co, USA.
  • Kaneko J J, Harvey J W & Brass M L (1997) Eds. Clinical Biochemistry of Domestic Animals. 5th edn. Academic Press, USA.
  • Duncan J R, Prasse K W & Mahaffey E A (1994) Veterinary Laboratory Medicine. Clinical Pathology. 3rd edn. Iowa University Press, USA.