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Blood biochemistry: aspartate aminotransferase
Synonym(s): AST, Serum AST, SAST, Glutamic oxalo-acetic transaminase, GOT, Serum GOT, SGOT
Overview
- Not organ specific, but highest levels in skeletal muscle, cardiac muscle, liver.
Uses
Alone
- Skeletal muscle damage.
- Cardiac ischemia.
- Liver damage.
Other points
- ALT Blood biochemistry: alanine aminotransferase (SGPT, ALT) is better for investigation of liver disease.
Sampling
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Tests
Methodologies
- Method and reference interval may vary between laboratories.
- Enzymatic methods commonly used.
Availability
- Widely available.
Technique intrinsic limitations
- Results only significant when interpreted in conjunction with other laboratory tests and clinical findings.
Result Data
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
Other sources of information
- Ettinger S J & Feldman E C (2000) Eds. Textbook of Veterinary Internal Medicine. 5th edn. W B Saunders & Co, USA.
- Kaneko J J, Harvey J W & Brass M L (1997) Eds. Clinical Biochemistry of Domestic Animals. 5th edn. Academic Press, USA.
- Duncan J R, Prasse K W & Mahaffey E A (1994) Veterinary Laboratory Medicine. Clinical Pathology. 3rd edn. Iowa University Press, USA.