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Primary seborrhea
Introduction
- Rare, inherited disorder of keratinization or cornification.
- Signs: scaly skin, often greasy, often malodorous, comedo formation.
- Prognosis: incurable, depends on severity.
Presenting signs
- Dry, flaky skin and dull coat +/- greasy malodorous skin, comedones, crusts
. - Secondary bacterial or yeast infection +/- associated pruritus.
- Ceruminous otitis externa Otitis externa.
Age predisposition
- Severe form by 2-3 days of age.
- Mild form noticeable by 6 weeks of age.
Breed/Species predisposition
- Persian Persian longhair.
- Himalayan
. - Exotic shorthair Exotic shorthair.
Cost considerations
- Lifelong therapy needed.
Pathogenesis
Etiology
- Inherited condition in Persian cats (?autosomal recessive). Any sex and color can be affected.
Pathophysiology
- Genetically determined trait, causing uncharacterized cell defect → excessive epidermal cell turnover.
Timecourse
- Present at birth.
- Lifelong.
- Worsens over time.
Diagnosis
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Treatment
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Prevention
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Outcomes
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Paradis M & Scott D W (1990) Hereditary primary seborrhea oleosa in Persian Cats. Feline Practice 19, 17.
Other sources of information
- Miller W H, Griffin C E & Campbell K L (2013) Small Animal Dermatology. Philadelphia, W B Saunders. pp 576-567. ISBN 978-1-4160-0028-0 (the standard dermatology text).
- Kwochka K W (1993) Keratinization abnormalities - understanding the mechanism of scale formation. In: Advances in Veterinary Dermatology. Volume 2. Eds: P J Ihrke et al. New York: Pergamon Press. pp 91.