Alprazolam in Cats (Felis) | Vetlexicon
felis - Articles

Alprazolam

ISSN 2398-2950

Contributor(s) :


Introduction

Name

  • Alprazolam/Xanax.

Class of drug

  • Benzodiazepine.

Description

Chemical name

  • 8-chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine

Molecular formula

  • C17H3ClN4

Molecular weight

  • 308.769

Physical properties

  • Solid.

Storage requirements

  • Alprazolam is stable under standard storage conditions when recommended maintaining the medication in tightly closed container kept in a dry and well ventilated space.

Uses

Subscribe To View

This article is available to subscribers.

Try a free trial today or contact us for more information.

Administration

Subscribe To View

This article is available to subscribers.

Try a free trial today or contact us for more information.

Pharmacokinetics

Subscribe To View

This article is available to subscribers.

Try a free trial today or contact us for more information.

Precautions

Subscribe To View

This article is available to subscribers.

Try a free trial today or contact us for more information.

Withdrawal Periods

Subscribe To View

This article is available to subscribers.

Try a free trial today or contact us for more information.

Adverse Reactions

Subscribe To View

This article is available to subscribers.

Try a free trial today or contact us for more information.

Further Reading

Publications

Refereed Papers

  • Recent references from VetMedResource and PubMed.
  • Bushnell G A et al (2017) Simultaneous antidepressant and bendzodiazepine new use and subsequent long-term benzodiazepine use in adults with depression, United States, 2001-2014). JAMA Psychiatry 74 (7), 747-735 PubMed.
  • Baldwin D S et al (2013) Benzodiazepines: Risks and benefits. A reconsideration. J Psychopharm 27 (11), 867-971 PubMed.
  • Soler L I, Boix A, Lauroba J, Colom H & Domenech J (2012) Transdermal delivery of alprazolam from a monolithic patch: formulation based on in vitro characterization. Drug Dev Ind Pharm 38 (10), 1171-1178 PubMed.
  • Singh A P, Saraf S K & Saraf S A (2012) SLN approach for nose-to-brain delivery of alprazolam. Drug Deliv Transl Res (6), 498-507 PubMed.
  • Ibáñez M, Anzola B (2009) Use of fluoxetine, diazepam, and behaviour modification as therapy for treatment of anxiety-related disorders in dogs. J Vet Behav Clin Appl Res 4, 223-229.
  • Sherman B L, Mills D S (2008) Canine anxieties and phobias: An update on separation anxiety and noise aversions.  Vet Clin North Am Sm Anim Pract 38, 1081-1106 PubMed.
  • Crowell-Davis S L et al (2003) Use of clomipramine, alprazolam, and behaviour modification for treatment of storm phobia in dogs. JAVMA 222 (6),744-748 PubMed.
  • Verster J C, Volkerts E R (2004) Clinical pharmacology, clinical efficacy, and behavioral toxicity of alprazolam: a review of the literature. CNS Drug Reviews 10, 45-76 PubMed.

Other sources of information

  • Ramsey I (2017) Alpraxolam. In: BSAVA Small Animal Formulary. 9th edn. pp 12.
  • Overall K L (2013) Manual of Clinical Behavioral Medicine for Dogs and Cats. Elsevier.