Oxytocin in Reptiles | Vetlexicon
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Oxytocin


Synonym(s): Pitocin, Syntocinon, Oxytocin S

Introduction

Name

  • Oxytocin.

Class of drug

  • Hormone.

Description

Chemical name

  • 1-({(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-(4-hydroxybenzyl)-13-[(1S)-1-methylpropyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-prolyl-L-leucylglycinamide.

Molecular formula

  • C43H66N12O12S2.

Molecular weight

  • 1007.19.

Physical properties

  • White powder, soluble in water.
  • One unit is equivalent of approximately 2-2.2 µg of pure hormone.
  • The commercially available preparations are highly purified and have virtually no antidiuretic or vasopressor activity.

Storage requirements

  • Room temperature.
  • Avoid freezing.

Uses

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Administration

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Pharmacokinetics

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Precautions

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Withdrawal Periods

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Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Di Ianni F, Parmigiani E, Pelizzone I et al (2014) Comparison between intramuscular and intravenous administration of oxytocin in captive-bred red-eared sliders (Trachemys scripta elegans) with non-obstructive egg retention. J Exotic Pet Med 23 (1), 79-84 SciDirect.
  • Tucker J K, Thomas D L & Rose J (2007) Oxytocin dosage in turtles. Chelonian Cons Biol 6 (2), 321-324 BioOne.

Other sources of information

  • Meredith A (2015) Ed BSAVA Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, UK. pp 338.
  • Plumb D (2015) Plumb’s Veterinary Drug Handbook. 8th edn. Wiley-Blackwell. pp 1296.
  • McArthur S, Wilkinson R & Meyer J (2004) Medicine and Surgery of Tortoises and Turtles. Blackwell Publishing, UK. pp 579.
  • Mader D R (2006) Ed. Reptile Medicine and Surgery. Saunders Elsevier, USA. pp 1242.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.