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Cimetidine


Introduction

Name

  • Cimetidine.

Class of drug

  • H2 antihistamine.

Description

Chemical name

  • N-cyano-N'-methyl-N"-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidine.

Molecular formula

  • C10H16N6S.

Molecular weight

  • 252.34.

Physical properties

  • White to off-white, crystalline powder.
  • Unpleasant odor (subjective).
  • Sparingly soluble in water and soluble in alcohol.
  • Cimetidine HCl occurs as white, crystalline powder and is very soluble in water and soluble in alcohol.

Storage requirements

  • Protected from light and at room temperature.
  • Do not refrigerate injectable product.
  • Oral dosage forms should be stored in tight containers.

Uses

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Administration

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Pharmacokinetics

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Precautions

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Withdrawal Periods

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Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Plumb D C (2015) Plumb's Veterinary Drug Handbook. 8th edn. Wiley-Blackwell, USA. pp 1296.
  • Carpenter J W & Marion C J (2013) Exotic Animal Formulary. 4th edn. Elsevier Saunders, USA. pp 564.
  • Tennant B (1999) Small Animal Formulary. 3rd edn. BSAVA, UK.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.