reptile - Articles
Gentamicin
Synonym(s): Gentamicin sulphate, Garasol, Gentaject, Garacin, Clinagel Vet, Easotic, Otomax, Tiacil
Introduction
In the UK, Gentamicin is classified as category C (Caution) by the European Medicines Agency (EMA).
Name
- Gentamicin.
Class of drug
- Aminoglycoside antibiotic.
Description
Chemical name
- 2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol.
Molecular formula
- C21H43N5O7.
Molecular weight
- 477.59.
Physical properties
- White to buff powder that is soluble in water and insoluble in alcohol.
Storage requirements
- Injection and oral solutions should be stored at room temperature.
- Freezing or temperatures above 40°C/104°F should be avoided.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Chung T H, Yi S W, Kim B S et al (2017) Identification and antibiotic resistance profiling of bacterial isolates from septicaemic soft-shelled turtles (Pelodiscus sinensis). Veterinarni Medicina 62 (3), 169-177 VetMedResource.
- Rasmussen C, Allender M C, Phillips C A et al (2017) Multi-drug resistance patterns of enteric bacteria in two populations of free-ranging Eastern box turtles (Terrapene carolina carolina). J Zoo Wildl Med 48 (3), 708-715 PubMed.
- Shin D M, Hossain S, Wimalasena S H M P et al (2017) Antimicrobial resistance and virulence factors of Edwardsiella tarda isolated from pet turtles. Pakistan Vet J 37 (1), 85-89 VetMedResource.
- Dipineto L, Russo T P, Calabria M et al (2014) Oral flora of Python regius kept as pets. Lett Appl Microbiol 58 (5), 462-465 PubMed.
Other sources of information
- Meredith A (2015) Ed. BSAVA Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, UK. pp 338.
- Plumb D (2015) Plumb’s Veterinary Drug Handbook. 8th edn. Wiley-Blackwell, USA. pp 1296.
- Mader D R (2006) Ed. Reptile Medicine and Surgery. Saunders Elsevier, USA. pp 1242.
- McArthur S, Wilkinson R & Meyer J (2004) Medicine and Surgery of Tortoises and Turtles. Blackwell Publishing, UK. pp 579.
- European Medicines Agency (online) Categorisation of Antibiotics for Use in Animals for Prudent and Responsible Use. Website: www.ema.europa.eu (pdf download).
Organisation(s)
- National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.