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Furosemide


Synonym(s): Frusemide, Lasix, Dimazon, Frusecare, Frusol, Frusedale, Disal, Furotabs, Furoject, Furocot

Introduction

Name

  • Furosemide.

Class of drug

  • Loop diuretic.

Description

Chemical name

  • 4-chloro-N-[2-furylmethyl]-5-sulfa-moylanthranilic acid.

Molecular formula

  • C12H11ClN2O5S.

Molecular weight

  • 330.74.

Physical properties

  • Odorless, practically tasteless, white to slightly yellow, fine, crystalline powder.
  • Practically insoluble in water, sparingly soluble in alcohol and freely soluble in alkaline hydroxides.

Storage requirements

  • Tablets: store in light-resistant, well-closed containers at room temperature.
  • Oral solution: room temperature and protected from light and freezing.
  • Injection: room temperature. A precipitate may form if the injection is refrigerated, but will resolve when warmed (it does not alter potency).

Uses

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Administration

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Pharmacokinetics

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Precautions

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Withdrawal Periods

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Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Meredith A (2015) Ed. BSAVA Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, UK. pp 338.
  • Plumb D (2015) Plumb’s Veterinary Drug Handbook. 8th edn. Wiley-Blackwell. pp 1296.
  • Carpenter J W & Marion C J (2013) Exotic Animal Formulary. 4th edn. Saunders, USA.
  • Mayer J & Donnelly T M (2013) Clinical Veterinary Advisor: Birds and Exotic Pets. Elsevier, USA. pp 752.
  • McArthur S, Wilkinson R, Meyer J (2004) Medicine and Surgery of Tortoises and Turtles. Blackwell Publishing, UK. pp 579.
  • Girling S J & Raiti P (2004) BSAVA Manual of Reptiles. BSAVA, UK. pp 383.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.