Sulfadimethoxine
Synonym(s): Sulphadimethoxine
Introduction
Name
- Sulfadimethoxine.
Class of drug
- Sulfonamide antibiotic (long-acting).
- Generally potentiated with trimethoprim.
Description
Chemical name
- 4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide.
Molecular formula
- C12H14N4O4S.
Molecular weight
- 310.32.
Physical properties
- Odorless or almost odorless, creamy white powder.
- It is very slightly soluble in water and slightly soluble in alcohol.
Storage requirements
- Store at room temperature and protected from light.
- If crystals form due to exposure to cold temperatures, either warm the vial or store at room temperature for several days to resolubolize the drug; efficacy is not impaired by this process.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Sledge D G, Bolin S T, Lim A et al (2011) Outbreaks of severe enteric disease associated with Eimeria furonis infection in ferrets (Mustela putorius furo) of 3 densely populated groups. JAVMA 239 (12), 1584-1588 VetMedResource.
Other sources of information
- Johnson-Delaney C A (2017) Ferret Medicine and Surgery. CRC Press, USA. pp 514.
- Meredith A (2015) Ed. BSAVA Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, UK. pp 338.
- Plumb D (2015) Plumb’s Veterinary Drug Handbook. 8th edn. Wiley-Blackwell. pp 1296.
- Fox J G & Marini R P (2014) Eds. Biology and Diseases of the Ferret. 3rd edn. Wiley Blackwell, USA. pp 835.
- Mayer J & Donnelly T M (2013) Clinical Veterinary Advisor: Birds and Exotic Pets. Elsevier, USA. pp 752.
- Belvins D I (1999) Veterinary Pharmaceuticals and Biologicals. 11th edn. Medical Economics.
- Bishop Y (1998) Ed. The Veterinary Formulary. 4th edn. British Veterinary Association and Royal Pharmaceutical Society, UK.
Organisation(s)
- National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.