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Flumazenil

ISSN 2398-2985


Synonym(s): Flumazenilum, Flumazepil, Romazicon, Flumazen, Anexate, Lanexat, Flumage

Introduction

Name

  • Flumazenil.

Class of drug

  • Selective benzodiazepine receptor antagonist.

Description

Chemical name

  • ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate.

Molecular formula

  • C15H14FN3O3.

Molecular weight

  • 303.29.

Physical properties

  • White to off-white crystalline compound, insoluble in water but soluble in acidic aqueous solutions.

Storage requirements

  • Once drawn into a syringe or mixed with solutions, discard after 24 h.
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Uses

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Administration

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Pharmacokinetics

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Precautions

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Withdrawal Periods

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Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Hawkins M G & Pascoe P J (2012) Anesthesia, Analgesia and Sedation of Small Mammals. In: Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery. 3rd edn. Eds: Quesenberry K E & Carpenter J W. Elsevier, USA. pp 429-451.
  • Plumb D C (2008) Plumb's Veterinary Drug Handbook. 6th edn. Blackwell Publishing, USA. pp 1296.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.