Flumazenil
Synonym(s): Flumazenilum, Flumazepil, Romazicon, Flumazen, Anexate, Lanexat, Flumage
Introduction
Name
- Flumazenil.
Class of drug
- Selective benzodiazepine receptor antagonist.
Description
Chemical name
- ethyl 8-fluoro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate.
Molecular formula
- C15H14FN3O3.
Molecular weight
- 303.29.
Physical properties
- White to off-white crystalline compound, insoluble in water but soluble in acidic aqueous solutions.
Storage requirements
- Once drawn into a syringe or mixed with solutions, discard after 24 h.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
Other sources of information
- Hawkins M G & Pascoe P J (2012) Anesthesia, Analgesia and Sedation of Small Mammals. In: Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery. 3rd edn. Eds: Quesenberry K E & Carpenter J W. Elsevier, USA. pp 429-451.
- Plumb D C (2008) Plumb's Veterinary Drug Handbook. 6th edn. Blackwell Publishing, USA. pp 1296.
Organisation(s)
- National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.