Hematology: eosinophil in Ferrets | Vetlexicon
ferret - Articles

Hematology: eosinophil

ISSN 2398-2985


Overview

  • A granular leukocyte with bilobed or U-shaped nucleus and cytoplasm containing round to oval,  orange to pink (eosinophilic) granules of uniform size.
  • Eosinophils are attracted into tissue primarily by histamine (mast cells and basophils) and lymphokine (lymphocytes) to neutralize histamine, serotonin and bradykinin resulting in an anti-inflammatory effect. Peroxidase, present in specific eosinophilic granules, exerts some anti-inflammatory effect at sites of antigen-antibody interaction, even when histamine is not involved.
  • Other functions are fibrin degradation (profibrinolysin produced by developing eosinophils in the bone marrow), phagocytosis and detoxification.

Uses

Alone

  • Measuring circulating eosinophil can give a guide to presence of:
    • Inflammatory and parasitic conditions.
    • Allergic conditions.

Other points

  • Kinetics: reservoir of 300-400 eosinophils in bone marrow (75% mature) for every eosinophil in circulating blood.
  • When eosinophilia is detected, it is recommended to perform a fecal parasitological test and the skin and hair coat should be inspected for ectoparasites.

Sampling

Subscribe To View

This article is available to subscribers.

Try a free trial today or contact us for more information.

Tests

Result Data

Subscribe To View

This article is available to subscribers.

Try a free trial today or contact us for more information.

Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Hein J, Spreyer F, Sauter-Louis C et al (2012) Reference ranges for laboratory parameters in ferrets. Vet Rec 171, 218 PubMed.

Other sources of information

  • Mayer J & Donnelly T M (2013) Clinical Veterinary Advisor: Birds and Exotic Pets. Elsevier, USA. pp 752.
  • Campbell T W & Ellis C K (2007) Avian and Exotic Hematology and Cytology. 3rd edn. Wiley-Blackwell. ISBN: 978-0813818115.
  • Feldman B F, Zinkl J G & Jain N C (eds) (2000) Schalm's Veterinary Hematology. 5th edn. Lippincott, Williams & Wilkins, USA.
  • Fudge A M (1999) Laboratory Medicine. Avian and Exotic Pets. W B Saunders Co. ISBN: 0721 676 790.