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Blood biochemistry: lactate dehydrogenase
Synonym(s): LD, LDH, Serum LDH, SLDH
Overview
- May be divided into isoenzymes found principally in skeletal muscle, cardiac muscle, liver and red blood cells - not organ specific, but useful in assessment of tissue damage.
- Longer half-life than creatine kinase.
Uses
Alone
- Skeletal muscle damage.
- Cardiac muscle damage.
- Liver damage.
Other points
- Always combine with CK.
Sampling
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Tests
Methodologies
- Varies between laboratories (electrophoresis needed for LDH isoenymes).
Availability
- Widely available.
Technique intrinsic limitations
- Test results most useful when interpreted in conjunction with other laboratory results and clinical findings.
- LDH without isoenzymes is so non-specific that it is rarely interpretively useful.
Result Data
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Further Reading
Publications
Refereed Papers
- Recent references from PubMed and VetMedResource.
Other sources of information
- Wesche P (2014) Clinical Pathology. In: BSAVA Manual of Rabbit Medicine. Eds: Meredith A & Lord B. BSAVA, UK. pp 124-137.