Tropicamide
Introduction
Name
- Tropicamide.
Description
Chemical name
- N-ethyl-3-hydroxy-2-phenyl-N- (pyridin-4-ylmethyl) propanamide.
Molecular formula
- C17 H20 N2 O2 .
Molecular weight
- 284.35.
Physical properties
- Topical eye drop.
Storage requirements
- Depends on the specific preparation, eg:
- Mydriacyl 0.5%:
- Do not store >25°C.
- Do not refrigerate or freeze.
- Keep container in the outer carton.
- Keep container tightly closed.
- Discard contents 4 weeks after opening.
- Minims 0.5% and 1% tropicamide:
- Store <25°C.
- Do not freeze.
- Protect from light.
- Mydriacyl 0.5%:
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Selk Ghaffari M, Sabzevari A & Radmehr B (2009) Effect of topical 1% tropicamide on Schirmer tear test results in clinically normal horses. Vet Ophthal 12 (6), 369-371 PubMed.
- Gelatt K N, Gum G G & Mackay E (1995) Evaluation of mydriatics in horses. Vet Comp Ophthal 5, 104-107.
Other sources of information
- Matthews A (2004) Ophthalmic Therapeutics. In: Equine Clinical Pharmacology. Eds: Bertone J & Horspool L. pp 217-246.
- Report a Suspect Adverse Reaction. Veterinary Medicines Directorate. Website: www.vmd.defra.gov.uk/adversereactionreporting.