equis - Articles
Timolol maleate
Introduction
Name
- Timolol maleate.
Description
Chemical name
- (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol.
Molecular formula
- C13 H24 N4 O3 S.
Molecular weight
- 316.42.
Physical properties
- Comes as a solution for administration to the eye.
Storage requirements
- Follow datasheet instructions.
- Do not store >25°C.
- Once opened use within 4 weeks.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Willis A M, Robbin T E et al (2001) Effect of topical administration of 2% dorzolamide hydrochloride or 2% dorzolamide hydrochloride-0.5% timolol maleate on intraocular pressure in clinically normal horses. Am J Vet Res 62 (5), 709-713 PubMed.
- Van Der Woerdt A, Wilkie D A, Gilger B C, Strauch S M & Orczeck S M (2000) Effect of single- and multiple-dose 0.5% timolol maleate on intraocular pressure and pupil size in female horses. Vet Ophthal 3 (2-3), 165-168 PubMed.
Other sources of information
- FEI Clean Sport Prohibited Substances Database. Website: prohibitedsubstancesdatabase.feicleansport.org.
- Report a Suspect Adverse Reaction. Veterinary Medicines Directorate. Website: www.vmd.defra.gov.uk.