Suxibuzone in Horses (Equis) | Vetlexicon
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Suxibuzone


Introduction

Name

  • Suxibuzone.

Class of drug

  • Non-steroidal anti-inflammatory drug.
  • Pyrazolidine.

Description

  • Slow infusion of sodium bicarbonate has been recommended. This alkalization increases clearance of the drug.
  • Supportive therapy.
  • Gastroprotectants.

Uses

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Administration

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Pharmacokinetics

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Precautions

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Withdrawal Periods

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Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Sabate D, Homedes J, Salichs M et al (2009) Multicentre, controlled, randomised and blinded field study comparing efficacy of suxibuzone and phenylbutazone in lame horses. Equine Vet J 41 (7), 700-705 PubMed.
  • Jaraiz V, Rodriguez C & San Andres M D (1999) Pharmacokinetics and bioequivalence of two suxibuzone oral dosage forms in horses. J Vet Pharm Ther 22 (4), 247-254 PubMed.
  • Homedes J, Sabate D & Mayos I (1997) General and gastrointestinal tolerance of suxibuzone orally administered to horses, compared to phenylbutazone. J Vet Pharm Ther 20 (Supp 1), 163-164.
  • Sabate D, Homedes J & Mayos I (1997) Comparative study of the clinical efficacy of suxibuzone and phenylbutazone in the treatment of musculoskeletal inflammatory disorders in horses. J Vet Pharm Ther 20, 162-163.
  • Delbeke F T, Vynckier L & Debackere M (1993) The disposition of suxibuzone in the horse. J Vet Pharm Ther 16 (3), 283-290 PubMed.
  • Tobin T, Chay S & Kamerling S (1986) Phenylbutazone in the horse: a review. J Vet Pharm Ther 9, 1-25.

Other sources of information

  • Kollias-Baker C & Cox K (2004) Non-steroidal Anti-inflammatory Drugs. In: Equine Clinical Pharmacology. Eds: Bertone J J & Horspool L J I. Saunders Elsevier, USA. pp 247-266.
  • Danilon Equidos® SPC.