Norepinephrine
Synonym(s): Noradrenaline
Introduction
Name
- Norepinephrine (as acid tartrate).
Class of drug
- Sympathomimetic.
- Catecholamine.
- Vasopressor.
- Inotrope.
Description
Chemical name
- 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol.
Molecular formula
- C8H11NO3.
Molecular weight
- 169.18 g (337.3 g as acid tartrate).
Physical properties
- Clear, colorless solution.
- Available as 1:1000 single use ampule.
Storage requirements
- Store <25°C.
- Protect from light.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Dickey E J, McKenzie H C & Furr M O (2010) Use of pressor therapy in 34 hypotensive critically ill neonatal foals. Aus Vet J 88, 472-477 PubMed.
- Craig C A, Haskins S C & Hildebrand S V (2007) The cardiopulmonary effects of dobutamine and norepinephrine in isoflurane-anesthetized foals. Vet Anaes Analg 34, 367-377 PubMed.
- Valverde A, Giguère S, Sanchez C L et al (2006) Effects of dobutamine, norepinephrine, and vasopressin on cardiovascular function in anesthetized neonatal foals with induced hypotension. Am J Vet Res 67, 1730-1737 PubMed.
- Corley K T, McKenzie H C III, Amoroso L M et al (2000) Initial Experience with Norepinephrine Infusion in Hypotensive Critically III Foals. J Vet Em Crit Care 10, 267-276.
Other sources of information
- Levophed® summary of product characteristics (SPC)