Norepinephrine in Horses (Equis) | Vetlexicon
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Norepinephrine

ISSN 2398-2977


Synonym(s): Noradrenaline

Introduction

Name

  • Norepinephrine (as acid tartrate).

Class of drug

  • Sympathomimetic.
  • Catecholamine.
  • Vasopressor.
  • Inotrope.

Description

Chemical name

  • 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol.

Molecular formula

  • C8H11NO3.

Molecular weight

  • 169.18 g (337.3 g as acid tartrate).

Physical properties

  • Clear, colorless solution.
  • Available as 1:1000 single use ampule.

Storage requirements

  • Store <25°C.
  • Protect from light.

Uses

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Administration

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Pharmacokinetics

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Precautions

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Withdrawal Periods

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Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Dickey E J, McKenzie H C & Furr M O (2010) Use of pressor therapy in 34 hypotensive critically ill neonatal foals. Aus Vet J 88, 472-477 PubMed.
  • Craig C A, Haskins S C & Hildebrand S V (2007) The cardiopulmonary effects of dobutamine and norepinephrine in isoflurane-anesthetized foals. Vet Anaes Analg 34, 367-377 PubMed.
  • Valverde A, Giguère S, Sanchez C L et al (2006) Effects of dobutamine, norepinephrine, and vasopressin on cardiovascular function in anesthetized neonatal foals with induced hypotension. Am J Vet Res 67, 1730-1737 PubMed.
  • Corley K T, McKenzie H C III, Amoroso L M et al (2000) Initial Experience with Norepinephrine Infusion in Hypotensive Critically III Foals. J Vet Em Crit Care 10, 267-276.

Other sources of information

  • Levophed® summary of product characteristics (SPC)