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Meloxicam


Introduction

Name

  • Meloxicam.

Class of drug

  • Non-steroidal anti-inflammatory drug; COX-2 preferential.
  • Enolic acid.

Description

  • Supportive therapy.
  • Gastroprotectants.

Uses

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Administration

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Pharmacokinetics

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Precautions

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Withdrawal Periods

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Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource
  • Burns P J, Morrow C, Gilley R M et al (2010) Evaluation of pharmacokinetic-pharmacodynamic relationships for BioRelease meloxicam formulations in horses. J Eq Vet Sc 30 (10), 539-544.
  • De Grauw J C, van der Lest C H A, Brama P A J et al (2009) In vivo effects of meloxicam on inflammatory mediators, MMP activity and cartilage biomarkers in equine joints with acute synovitis. Eq Vet J 41 (7), 693-699 PubMed.
  • Little D, Brown S A, Campbell N B, Moeser A J, Davis J L & Blikslager A T (2007) Effects of the cyclooxygenase inhibitor meloxicam on recovery of ischemia-injured equine jejunum. Am J Vet Res 68 (6), 614-624 PubMed.
  • Friton G M, Phillip H, Kleemann R et al (2006) Investigation of the clinical efficacy, safety and palatability of meloxicam (Metacam®) treatment in horses with musculoskeletal disorders. Pferdeheilkunde 22 (4), 420-426.
  • Sinclair M D, Mealey K L, Matthews N S, Peck K E, Taylor T S & Bennett B S (2006) Comparative pharmacokinetics of meloxicam in clinically normal horses and donkeys.Am J Vet Res 67 (6), 1082-1085 PubMed.
  • Toutain P L, Reymond N, Laroute V et al (2004) Pharmacokinetics of meloxicam in plasma and urine in horses. Am J Vet Res 65 (11), 1542-1547 PubMed.
  • Lees P, Sedgewick A D, Higgins A J et al (1991) Pharmacokinetics and pharmacodynamics of miloxicam in the horse. Br Vet J 147 (2), 97-108 PubMed.

Other sources of information

  • Plumb D C (2011) Veterinary Drug handbook. 7th edn. Wiley-Blackwell, USA.
  • Hanson P D & Maddison J E (2008) Non-steroidal anti-inflammatory drugs and chondroprotective agents. In: Small Animal Clinical Pharmacology. 2nd edn. Eds: Maddison J E, Page S W & Church D B. Saunders Elsevier, USA. pp 287-309.