equis - Articles
Dorzolamide
Introduction
Name
- Dorzolamide hydrochloride.
Class of drug
- Carbonic anhydrase inhibitor.
Description
Chemical name
- (4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide.
Molecular formula
- C10 H16 N2 O4 S3 .
Molecular weight
- 324.4.
Physical properties
- Clear, colorless, slightly viscous solution.
Storage requirements
- Once opened use within 28 days.
- Protect from light.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Willis A M, Robbin T E et al (2001) Effect of topical administration of 2% dorzolamide hydrochloride or 2% dorzolamide hydrochloride-0.5% timolol maleate on intraocular pressure in clinically normal horses. Am J Vet Res 62 (5), 709-713 PubMed.
Other sources of information
- Gilger B C (2005) Equine Ophthalmology. Saunders. pp 334. ISBN: 978-1416053842.
- Matthews A (2004) Ophthalmic Therapeutics. In: Equine Clinical Pharmacology. Eds: Bertone J & Horspool L. pp 217-246.
- FEI Clean Sport Prohibited Substances Database. Website: prohibitedsubstancesdatabase.feicleansport.org.
- Report a Suspect Adverse Reaction.Veterinary Medicines Directorate. Website: www.vmd.defra.gov.uk/adversereactionreporting.