Amiodarone in Horses (Equis) | Vetlexicon
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Amiodarone

ISSN 2398-2977

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Introduction

Name

  • Amiodarone.

Class of drug

  • Class 3 antiarrhythmic agent.

Description

Chemical name

  • (2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodophenoxy}ethyl)diethylamine.

Molecular formula

  • C25H29I2NO3.

Molecular weight

  • 645.3 g/mol.

Physical properties

  • White-cream crystalline powder.

Storage requirements

  • Room temperature.

Uses

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Administration

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Pharmacokinetics

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Precautions

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Withdrawal Periods

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Adverse Reactions

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Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Premont A, Balthes S, Marr C M & Jeevaratnam K (2022) Fundamentals of arrhythmogenic mechanisms and treatment strategies for equine atrial fibrillation. Equine Vet J 54 (2), 262-282 PubMed.
  • Saljic A, Jespersen T & Buhl R (2022) Anti-arrhythmic investigations in large animal models of atrial fibrillation. Br J Pharmacol 179 (5), 838-858 PubMed.
  • Decloedt A, Van Steenkiste G, Vera L, Buhl R & van Loon G (2021) Atrial fibrillation in horses Part 2: Diagnosis, treatment and prognosis. Vet J 268, 105594 PubMed.
  • Decloedt A, Van Steenkiste G, Vera L, Buhl R & van Loon G (2020) Atrial fibrillation in horses part 1: pathophysiology. Vet J 263, 105521 PubMed.
  • Redpath A & Bowen M (2019) Cardiac therapeutics in horses. Vet Clin North Am Equine Pract 35 (1), 217-241 PubMed.
  • Sleeper M M (2017) Equine cardiovascular therapeutics. Vet Clin North Am Equine Pract 33 (1), 163-179 PubMed.
  • Whelchel D D, Tennent-Brown B S, Coleman A E et al (2017) Treatment of supraventricular tachycardia in a horse. J Vet Emerg Crit Care (San Antonio) 27 (3), 362-368 PubMed.
  • McGurrin M K J (2015) The diagnosis and management of atrial fibrillation in the horse. Vet Med (Auckl) 26 (6), 83-90 PubMed.
  • De Clercq D, van Loon G, Baert K et al (2007) Effects of an adapted intravenous amiodarone treatment protocol in horses with atrial fibrillation. Equine Vet J 39 (4), 344-349 PubMed.
  • De Clercq D, van Loon G, Baert K V & Tavernier Rene (2006) Intravenous amiodarone treatment in horses with chronic atrial fibrillation. Vet J 172 (1), 129-134 PubMed.

Organisation(s)

  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.