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Alfaxalone


Introduction

Name

  • Alfaxalone.

Class of drug

  • Neuroactive steroid.
  • General anesthetic.

Uses

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Administration

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Pharmacokinetics

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Precautions

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Withdrawal Periods

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Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Goodwin W A, Keates H L, Pearson M & Pasloske K (2013) Alfaxalone and medetomidine intravenous infusion to maintain anaesthesia in colts undergoing field castration. Equine Vet J 45 (3), 315-319 PubMed.
  • Klöppel H & Leece L A (2011) Comparison of ketamine and alfaxalone for induction and maintenance of anaesthesia in ponies undergoing castration.Vet Anaesth Analg 38 (1), 37-43 PubMed.
  • Leece E A, Girard N M & Maddern K (2009) Alfaxalone in cyclodextrin for induction and maintenance of anaesthesia in ponies undergoing field castration. Vet Anaesth Analg 36 (5), 480-484 PubMed.

Other sources of information

  • Goodwin W, Keates H, Pasloske K et al (2009) Total Intravenous Anaesthesia (TIVA) in the Horse with Alfaxalone. In: Proc 10th WCVA (abstract). pp 87.
  • Goodwin W, Keates H & Pasloske K (2006) Plasma Pharmacokinetics and Pharmacodynamics of Alfaxalone in Horses after Intravenous Administration of the Anaesthetic Agent Alfaxan at 1 mg/kg. In: Proc 9th WCVA (abstract). pp 152. 
  • Pearson M, Keates H & Van Eps A (2006) A Cmparison between Alfaxalone in Cyclodextrin and Ketamine for Induction of Anaesthesia in Horses. In: Proc 9th WCVA. pp 152.