equis - Articles
CSF: cytology
Overview
- Changes most dramatically with inflammation, being more reliable in acute conditions.
- The type and number of cells helps identify cause CSF: cell count and differential .
Uses
Alone
- Diagnosis of central nervous system (CNS) inflammation.
In combination
- With protein electrophoresis: to differentiate inflammatory changes from other non-inflammatory causes in general.
Other points
- As CNS disease progresses, cytology of the cerebrospinal fluid (CSF) becomes a less reliable diagnostic tool.
Sampling
Subscribe To View
This article is available to subscribers.
Try a free trial today or contact us for more information.
Tests
Methodologies
- Total cell count with hemocytometer.
- Giemsa-stained smear of fluid directly or of cells concentrated by centrifugation, sedimentation, membrane filtration.
Availability
- Widely available.
Technique intrinsic limitations
- CSF samples can be contaminated with blood, this necessitates correction of cell count and differential CSF: cell count and differential .
- CSF cytology changes as CNS illness progresses.
Result Data
Subscribe To View
This article is available to subscribers.
Try a free trial today or contact us for more information.
Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Johnson P J & Constantinescu G M (2000) Collection of cerebrospinal fluid in horses. Equine Vet Educ 12, 7-12.
- Johnson P J & Constantinescu G M (2000) Analysis of cerebrospinal fluid in horses. Equine Vet Educ 12, 13-17.