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Atropine sulfate

obovis
Contributor(s):

Vetstream Ltd

Andrea Tarr

Synonym(s): DL-hyoscyamine


Introduction

Name

  • Atropine sulfate.
Few atropine products are licensed for use in cattle. Always check the product information and adhere to local rules.
 

Class of drug

  • Modulator of intestinal motility, antimuscarinic pre-anesthetic medication, mydriatic and cycloplegic.

Description

Chemical name

  • Endo-(+/-)-alpha-(hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester.
  • 1-alphaH,5-alphaH-tropan-3-alpha-ol(+/-)-tropate (ester).

Molecular formula

  • C17H23NO3.

Molecular weight

  • 289.38.

Physical properties

  • Clear, sterile solution.
  • Derived from Atropa belladonna (deadly nightshade) .

Storage requirements

  • <25°C/77°F.
  • Protect from light.

Uses

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Indications

Administration

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Precautions

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Withdrawal Period

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Adverse Reactions

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Further Reading

Publications

Refereed Papers

  • Recent references from PubMed and VetMedResource.
  • Haskell S R R, Payne M, Webb A, Riviere J & Craigmill A L (2005) FARAD Digest Antidotes in food animal practice. JAVMA 226 (6), 884 -887 Farad (pdf online)

Other sources of information

  • CFNP TAP Review (2002) Atropine Livestock. Website: www.ams.usda.gov (pdf online)
  • Derived from  The Veterinary Formulary  (1998) 4th edn. Ed: Bishop Y. British Veterinary Association and Royal Pharmaceutical Society.
  • Anon (1998) The European Agency for the Evaluation of Medicinal Products Atropine summary report. Website: www.ema.europa.eu (pdf online)
  • National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.

Organisation(s)

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