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Polyarthritis / polymyositis syndrome
Introduction
- Polyarthritis and polymyositis in combination seen particularly in Spaniel breeds.
- Cause: unknown but appears to be immune-mediated.
- Signs: stiffness, pain.
- Diagnosis: signs, cytology, histopathology.
- Treatment: immunosuppressive therapy.
- Prognosis: guarded.
Presenting signs
- Depression.
- Anorexia.
- Reluctance to move/stiffness.
Breed/Species predisposition
- Spaniel breeds
- American Cocker American Cocker Spaniel.
- Clumber Clumber Spaniel.
- Cocker English Cocker Spaniel.
- English springer English Springer Spaniel.
- Field Spaniel: Field.
- Welsh Spaniel: Welsh Springer.
- Conditions may be seen in combination in any breed.
Pathogenesis
Pathophysiology
- Believed to be immune-mediated condition.
Timecourse
- Days to weeks.
Diagnosis
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Treatment
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Prevention
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Outcomes
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Kornegay J N, Gorgacz E J, Dawe D L, Bowen J M, White N A, DeBuysscher E V (1980) Polymyositis in dogs. JAVMA 176 (5), 431-438 PubMed.
- Krum S H, Cardinet G H, Anderson B C & Holliday T A (1977) Polymyositis and polyarthritis associated with systemic lupus erythematosus in a dog. JAVMA 170 (1), 61-64 PubMed.