Phenylpropanolamine in Dogs (Canis) | Vetlexicon
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Phenylpropanolamine

ISSN 2398-2942


Synonym(s): Norephedrine hydrochloride, Propadrine hydrochloride, DL-Phenylpropanolamine hydrochloride, DL-Norephedrine hydrochloride, Norephedrine hydrochloride

Introduction

Name

  • Phenylpropanolamine.

Class of drug

  • Sympathomimetic amine.

Description

Chemical name

  • 4-(diphenylmethoxy)-1-methylpiperidine.

Molecular formula

  • C19H23NO.

Physical properties

  • Clear liquid.

Storage requirements

  • <25°C/77°F.
  • In a dry environment.
  • Do not store in fridge.

Uses

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Administration

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Pharmacokinetics

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Precautions

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Adverse Reactions

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Claeys S, Rustichelli F, Noël S & Hamaide A (2011) Clinical evaluation of a single daily dose of phenylpropanolamine in the treatment of urethral sphincter mechanism incompetence in the bitch. Can Vet J 52 (5),501-505 PubMed.
  • Peterson K L, Lee J A & Hovda L R (2011) Phenylpropanolamine toxicosis in dogs: 170 cases. J Am Vet Med Assoc 239 (11),1463-1469 PubMed.
  • Scott L, Leddy M, Bernay F & Davot J L (2002) Evaluation of phenylpropanolamine in the treatment of urethral sphincter mechanism incompetence in the bitch. JSAP 43, 493-496 PubMed.
  • White R A & Pomeroy C J (1989) Phenylpropanolamine: an alpha-adrenergic agent for the management of urinary incontinence in the bitch associated with urethral sphincter mechanism incompetence. Vet Rec 125 (19), 478-480 PubMed.

Other sources of information

  • Veterinary Medicines Directorate (2024) Summary of Product Characteristics: Propalin syrup. Wensite: www.vmd.defra.gov.uk (pdf download)
  • Plumb D C (2002) Veterinary Drug Handbook. 4th edn. Iowa State University Press, USA.
  • Tennant B (1999) Small Animal Formulary. 3rd edn. BSAVA, UK.