Phenylpropanolamine
Synonym(s): Norephedrine hydrochloride, Propadrine hydrochloride, DL-Phenylpropanolamine hydrochloride, DL-Norephedrine hydrochloride, Norephedrine hydrochloride
Introduction
Name
- Phenylpropanolamine.
Class of drug
- Sympathomimetic amine.
Description
Chemical name
- 4-(diphenylmethoxy)-1-methylpiperidine.
Molecular formula
- C19H23NO.
Physical properties
- Clear liquid.
Storage requirements
- <25°C/77°F.
- In a dry environment.
- Do not store in fridge.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Adverse Reactions
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
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Claeys S, Rustichelli F, Noël S & Hamaide A (2011) Clinical evaluation of a single daily dose of phenylpropanolamine in the treatment of urethral sphincter mechanism incompetence in the bitch. Can Vet J 52 (5),501-505 PubMed.
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Peterson K L, Lee J A & Hovda L R (2011) Phenylpropanolamine toxicosis in dogs: 170 cases. J Am Vet Med Assoc 239 (11),1463-1469 PubMed.
- Scott L, Leddy M, Bernay F & Davot J L (2002) Evaluation of phenylpropanolamine in the treatment of urethral sphincter mechanism incompetence in the bitch. JSAP 43, 493-496 PubMed.
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White R A & Pomeroy C J (1989) Phenylpropanolamine: an alpha-adrenergic agent for the management of urinary incontinence in the bitch associated with urethral sphincter mechanism incompetence. Vet Rec 125 (19), 478-480 PubMed.
Other sources of information
- Veterinary Medicines Directorate (2024) Summary of Product Characteristics: Propalin syrup. Wensite: www.vmd.defra.gov.uk (pdf download)
- Plumb D C (2002) Veterinary Drug Handbook. 4th edn. Iowa State University Press, USA.
- Tennant B (1999) Small Animal Formulary. 3rd edn. BSAVA, UK.