canis - Articles
Salivary gland: neoplasia
Introduction
- Unusual - adenocarcinoma most common type.
- Signs:
EitherFirm discrete enlargement of one of major salivary glands/occasionally with associated mucocele.
OrDiffuse thickened infiltration of oral mucosa developing from one of the minor glands. - Diagnosis: histopathology.
- Treatment: surgical resection if possible.
- Prognosis: guarded, risk of metastasis and local recurrence. In addition, adjacent neurovascular structures may be damaged.
Presenting signs
- Mass in cervical region.
- Firm discrete enlargement of major gland/diffuse thickened enlargement of oral mucosa developing from minor gland.
- Associated mucocele possible Salivary mucocele.
Age predisposition
- Older dogs (>10 years old).
Breed/Species predisposition
- Spaniels and Poodles predisposition.
Pathogenesis
Etiology
- Usually malignant.
- Adenocarcinoma Adenoma / adenocarcinoma.
Pathophysiology
- Usually primary tumors but metastasize to local lymph nodes readily.
- Distant metastases (lungs/bone) possible.
Timecourse
- Weeks to months.
Diagnosis
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Treatment
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Prevention
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Outcomes
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Hammer A et al (2001) Salivary gland neoplasia in the dog and cat: survival times and prognostic factors. JAAHA 37 (5), 478-482 PubMed.
- Carberry C A, Flander J A, Harvey H J & Ryan A M (1988) Salivary gland tumors in dogs and cats - a literature and case review. JAAHA 24 (5), 561-7 VetMedResource.
Other sources of information
- Dunning D (2003)Oral cavity: tongue, lips, cheeks, pharynx, and salivary glands.In:Textbook of Small Animal Surgery. 3rd edn. Slatter D (ed), W B Saunders, Philadelphia, pp 553-561.
- Hedlund C S (2002)Surgery of the oral cavity and oropharynx.In:Small Animal Surgery.2nd edn, T W Fossum (ed), Mosby, St. Louis, pp 274-307.
- Knecht C D (1998)Salivary glands.In:Current techniques in Small Animal Surgery.4th edn, Bojrab M J (ed), Williams and Wilkins, Baltimore, pp183-186.