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Urinalysis: specific gravity

ISSN 2398-2942

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Overview

  • Measure kidneys' ability to concentrate and dilute urine.

Uses

Alone

  • Assessment of kidneys' ability to alter specific gravity of glomerular filtrate.

In combination

  • With other tests of renal function in assessment of renal function.

Sampling

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Tests

Methodologies

Refractometer (most common)

  • Single drop placed on glass surface; reading relative to specific gravity of distilled water (= 1).

Urinometer

  • Need large volume (15-45 ml), but can dilute and recalculate specific gravity reading.
  • Three-quarter fill cylinder then insert urinometer and read scale at interface of air with urine; the scale reading represents the 2nd and 3rd decimal placing, eg reading of 25 = 1.025.

Dipstick

  • Results do not correlate well with refractometer.
  • Inaccurate for non-human urine/disregard for animal urine.

Availability

  • Standard practice laboratory technique.

Technique intrinsic limitations

  • Cannot interpret results in isolation from other urinalysis results and lab tests.
  • Single random result outside normal reference range cannot establish diagnosis.

Result Data

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Further Reading

Publications

Refereed papers

  • Recent references from VetMedResource and PubMed.
  • Brobst D (1989) Urinalysis and associated laboratory procedures. Vet Clin North Am Small Anim Pract 19 (5), 929-949.
  • McCaw D L, Fleming E J & Mikiciuk M G (1989) Interpreting the results of urinalysis - a key to diagnosing renal disorders. Vet Med 84 (3), 281-286.

Other sources of information

  • Kaneko J J (1997) Clinical Biochemistry of Domestic Animals. 5th edn. Eds: Harvey J W & Bruss M L. Academic Press, USA.
  • Duncan J R, Prasse K W & Mahaffy E A (1994) Veterinary Laboratory Medicine Clinical Pathology. 3rd edn. Iowa University Press, USA.