canis - Articles
Blood biochemistry: phosphate
Synonym(s): PO4
Overview
- Major component of bones and teeth (80-85% of phosphorus is bound there).
- Major intracellular anion.
- Also important in energy metabolism and acid-base balance.
- Parathyroid hormone is main regulator - excreted through kidneys.
- Marker of bone disease, parathyroid function and renal function.
Uses
In combination
- Primary hyperparathyroidism Hyperparathyroidism (primary).
- Hypercalcemia of malignancy Hypercalcemia: overview.
- Renal failure Kidney: chronic kidney disease (CKD).
- Osteolytic bone tumor Bone: neoplasia.
- Calciferol poisoning.
Sampling
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Tests
Methodologies
- Colorimetric assay for inorganic phosphate (organic forms not routinely evaluated).
Availability
- Widely available at commercial laboratories.
Technique intrinsic limitations
- Test results only significant in conjunction with other laboratory results and clinical findings.
Result Data
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Further Reading
Publications
Refereed papers
- Recent references from VetMedResource and PubMed.
Other sources of information
- Ettinger S J & Feldman E C (2000) Eds. Textbook of Veterinary Internal Medicine. 5th edn. W B Saunders & Co, USA.
- Kaneko J J, Harvey J W & Brass M L (1997) Eds. Clinical Biochemistry of Domestic Animals. 5th edn. Academic Press, USA.
- Duncan J R, Prasse K W & Mahaffey E A (1994) Veterinary Laboratory Medicine. Clinical Pathology. 3rd edn. Iowa University Press, USA.