canis - Articles
Blood biochemistry: amylase
Synonym(s): Alpha Amylase, AMS
Overview
- Plasma levels derived mainly from small intestine (duodenal mucosa), liver and pancreas → excreted through kidneys.
- Inflammation of pancreas release large amounts.
Uses
In combination
- Diagnosis of pancreatitis Pancreatitis: acute with lipase Blood biochemistry: lipase and TLI Blood biochemistry: trypsin-like immunoreactivity.
Sampling
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Tests
Methodologies
- Amyloclastic method.
- Saccharogenic methods not appropriate for use on canine serum.
Availability
- Widely available.
Validity
Sensitivity
- Considered sensitive for canine pancreatitis but false negative and false positive results may occur.
Specificity
- Not as specific for pancreatitis as lipase or TLI Blood biochemistry: lipase.
- May see increases commonly with renal failure, gastrointestinal disease, and/or hepatobiliary disease.
Technique intrinsic limitations
- Results most significant in conjunction with other laboratory results and clinical findings.
Result Data
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Further Reading
Publications
Refereed papers
- Recent references from VetMedResource and PubMed.
- Simpson K W, Batt R M, McLean L et al (1989) Circulating concetrations of trypsin-like immunoreactivity and activities of lipase and amylase after pancreatic duct ligation in dogs. Am J Vet Res 50, 629.
- Hall T A & Macy D W (1988) Acute pancreatitis. Comp Cont Educ Pract Vet 10, 403.
Other sources of information
- Ettinger S J & Feldman E C (2000) Eds. Textbook of Veterinary Internal Medicine.5th edn. W B Saunders & Co, USA.
- Kaneko J J, Harvey J W & Brass M L (1997) Eds. Clinical Biochemistry of Domestic Animals. 5th edn. Academic Press, USA.
- Duncan J R, Prasse K W & Mahaffey E A (1994) Veterinary Laboratory Medicine. Clinical Pathology. 3rd edn. Iowa University Press, USA.