canis - Articles
Pancreatitis: chronic
Introduction
- Chronic pancreatitis in the dog is not commonly diagnosed antemortem.
- It may develop as a sequelae to acute pancreatitis Pancreatitis: acute.
- Cause: usually unresolved acute pancreatitis.
- Signs: episodic signs of abdominal pain/vomiting or subclinical condition manifest as/resulting in diabetes mellitus or exocrine pancreatic insufficiency.
- Diagnosis: laboratory tests, ultrasonography, histopathology.
- Treatment: acute episodes as for acute pancreatitis; dietary modification, pancreatic enzyme supplementation.
- Prognosis: guarded unless underlying etiology identified and controlled.
Print off the owner factsheet on Pancreatitis Pancreatitis to give to your client.
Presenting signs
- Subclinical.
- Vomiting (intermittent).
- Anorexia.
- Weight loss.
- Diarrhea - (especially in case of EPI Exocrine pancreatic insufficiency ).
- Polyuria/polydipsia if diabetes mellitus Diabetes mellitus.
Acute presentation
- Recurrent episodes of acute pancreatitis Pancreatitis: acute.
- Jaundice.
Pathogenesis
Etiology
- Sequelae of unresolved acute pancreatitis Pancreatitis: acute.
Predisposing factors
General- High nutritional plane - high fat diets.
- Hereditary predisposition ?miniature Schnauzer Schnauzer: miniature Schnauzer, English Cocker spaniel English Cocker Spaniel.
- Obesity.
- Dietary indiscretion.
Pathophysiology
- Chronic damage to pancreatic tissue may → fibrosis and reduced pancreatic function:
- Diabetes mellitus Diabetes mellitus.
- Exocrine pancreatic insufficiency Exocrine pancreatic insufficiency.
Timecourse
- Months to years.
Diagnosis
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Treatment
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Prevention
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Outcomes
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Bostrom B M, Xenoulis P G, Newman S J, Pool R R, Fosgate G T & Steiner J M (2013) Chronic pancreatitis in dogs: a retrospective study of clinical, clinicopathological, and histopathological findings in 61 cases. Vet J 195 (1), 73-79 PubMed.
- Watson P J, Roulois A, Scase T, Holloway A & Herrtage M E (2011) Characterisation of chronic pancreatitis in English Cocker Spaniels. JVIM 25 (4), 797-804 PubMed.
- Watson P J, Archer J, Roulois A J, Scase T J & Herrtage M E (2010) Observational study of 14 cases of chronic pancreatitis in dogs. Vet Rec 167 (25), 968-976 PubMed.
- Watson P J, Roulois A J, Scase T, Johnston P E, Thompson H & Herrtage M (2007) Prevalence and breed distribution of chronic pancreatitis at post-mortem examination in first-opinion dogs. JSAP 48 (11), 609-618 PubMed.
- Mansfield C S & Jones B R (2000) Plasma and urinary trypsinogen activation peptide in healthy dogs, dogs with pancreatitis and dogs with other systemic diseases. Aust Vet J 78 (6), 416-422 PubMed.