Diarrhea: due to systemic illness
Introduction
- Cause: usually major organ dysfunction.
- Signs: diarrhea in association with signs of underlying disease.
- Diagnosis: identify underlying hepatic disease.
- Treatment: manage underlying condition and symptomatic treatment of disease.
- Prognosis: depends on ability to treat underlying disease.
Presenting signs
- Chronic diarrhea.
- Animal may be systematically unwell or show other signs of disease.
Pathogenesis
Pathophysiology
Congestive heart failure
- Elevated central venous pressure → abnormal drainage from intestine, blood and lymph → oedema → may cause increased intestinal permability and diarrhea.
- Portal hypertension → stasis in intestinal draining veins → impaired absorption and mucosal edema → lymphangiectasia.
- Impaired hepatic function/obstruction of bile duct → reduced delivery of bile acids to duodenum → impaired fat digestion/absorption → diarrhea.
Diagnosis
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Treatment
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Prevention
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Outcomes
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