canis - Articles
Diarrhea: chronic
Introduction
- Intractable/recurrent diarrhea of small or large bowel origin.
- Cause:
- Dietary intolerance Skin: food hypersensitivity.
- Parasites.
- Infection.
- Maldigestion Maldigestion.
- Malabsorption Malabsorption.
- Treatment: depends on etiology.
- Prognosis: guarded.
Presenting signs
- Variable dependent on etiology.
Breed/Species predisposition
- German Shepherd dog German Shepherd Dog - small bowel.
- Basenji Basenji - small bowel.
- Irish Setter
- small bowel. - Shar Pei Chinese Shar Pei - small bowel.
- Boxer Boxer - large bowel.
- Golden Retriever Retriever: Golden - large bowel (in UK).
Pathogenesis
Etiology
- See specific conditions.
Pathophysiology
- Impaired digestion/impaired absorption Malabsorption → presence of intraluminal complex molecules → osmotic diarrhea.
- Some bacterial toxins, and also metabolites of intraluminal bacterial digestion of nutrients, stimulate secretion of fluid from intestine → secretory diarrhea.
- Intestinal mucosal inflammation → increased mucosal permeability → diarrhea.
- Altered intestinal motility.
Timecourse
- Persisting >2 weeks.
Diagnosis
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Treatment
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Prevention
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Outcomes
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Ludlow C L (1995) Methods of testing small intestinal function. Vet Med 90 (10), 934-948 VetMedResource.
- Simpson J W (1992) Role of nutrition in aetiology and treatment of diarrhea. JSAP 33 (4), 167-171 VetMedResource.
- Batt R M & Hall E J (1989) Chronic enteropathies in the dog. JSAP 30 (1), 3-12 VetMedResource.
- Moon H W (1978) Mechanisms in the pathogenesis of diarrhea - a review. JAVMA 172 (4), 443-448 PubMed.
Other sources of information
- Simpson K W (1996) Small Intestinal Disease. In: BSAVA Manual of Canine and Feline Gastroenterology. J W Simpson, E Hall & D Thomas (editors), BSAVA, Cheltenham. p114.