Canine parvovirus in Dogs (Canis) | Vetlexicon
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Canine parvovirus

ISSN 2398-2942


Synonym(s): Parvo

Introduction

Classification

Taxonomy

  • Family: Parvoviridae.
  • Genus: Parvovirus.
  • CPV 1: also known as minute virus of canines.
  • CPV 2: several variants identified including CPV 2a, 2b and 2c.

Etymology

  • Latin: parvus- small.

Distribution

  • Worldwide.
  • For CPV 2 the proportion of the different variants (ie CPV 2a, 2b or 2c) depends on the country or geographical area.

Significance

  • Cause of acute generalized disease Parvovirus disease associated with CPV-2 characterized by sudden onset of diarrhea, vomiting, and fever.
  • Depression, lymphopenia, and dehydration occur.
  • Mortality is higher in puppies, especially in those <2 weeks old.
  • Puppies infected when 3-8 weeks old may develop myocarditis, sometimes without clinical signs of enteritis.

Active Forms

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Resting Forms

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Clinical Effects

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Diagnosis

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Zhou L, Wu H, Du M, Song H et al (2022) A canine-derived chimeric antibody with high neutralizing activity against canine parvovirus-2. AMB Express 12 (1), 76 PubMed.
  • Decaro N, Martella V, Elia G et al (2007) Tissue distribution of the antigenic variants of canine parvovirus type 2 in dogs. Vet Microbiol 121 (1-2), 39-44 PubMed.
  • Martella V, Decaro N & Buonavoglia (2006) Evolution of CPV-2 and impliance for antigenic/genetic characterisation. Virus Genes 33 (1), 11-13 PubMed.
  • Martella C, Cavalli A, Pratelli A et al (2004) A canine parvovirus mutant is spreading in Italy. J Clin Microbiol 42 (3), 1333-1336 PubMed.
  • Cohn L A, Rewerts J M, McCaw D et al (1999) Plasma granulocyte colony-stimulating factor concentrations in neutropenic, parvoviral enteritis-infected puppies. JVIM 13 (6), 581-586 PubMed.
  • Horiuchi M, Yamaguchi Y, Gojobori T et al (1998) Differences in the evolutionary pattern of feline panleukopenia virus and canine parvovirus. Virology 249 (2), 440-452 PubMed.
  • Houston D M, Ribble C S & Head L L (1996) Risk factors associated with parvovirus enteritis in dogs: 283 cases. JAVMA 208 (4), 542-546 PubMed.
  • Greenwood N M, Chalmers W S, Baxendale W et al (1995) Comparison of isolates of canine parvovirus by restriction enzyme analysis, and vaccine efficacy against field strains. Vet Rec 136 (3), 63-67 PubMed.

Other sources of information

  • Elanco Product information insert (2023) Canine Parvovirus Monoclonal Antibody. Website: www.elancolabels.com.
  • US Department of Agriculture (online). Center for Veterinary Biologics. Website: www.aphis.usda.gov.