Florfenicol
Synonym(s): Fluorinated synthetic analogue of the antibiotic thiamphenicol
Introduction
Name
- Florfenicol amine.
Class of drug
- Fluorinated synthetic analogue of the antibiotic thiamphenicol.
Description
Chemical name
- (1R,2S)-2-amino-3-fluoro-1-(4-methylsulfonylphenyl)propan-1-ol.
Molecular formula
- C������H������Cl���FNO���S
Molecular weight
- 358.21
Physical properties
- Topical gel.
Storage requirements
- Refrigerator.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Forster S L, Real T, Doucette K P et al (2018) A randomized placebo-controlled trial of the efficacy and safety of a terbinafine, florfenicol and betamethasone topical ear formulation in dogs for the treatment of bacterial and/or fungal otitis. BMC Vet Res 14 (1), 262 PubMed.
- King S B, Doucette K P, Seewald W et al (2018) A randomized, controlled, single-blinded multi-center evaluation of the efficacy and safety of a once weekly two dose otic gel containing florfenicol, terbinafine and betamethasone administered for the treatment of canine otitis externa. BMC Vet Res 14 (1), 307 PubMed.
Other sources of information
- Elanco: www.elanco.us/products-services/dogs/osurnia
- Bayer: www.bayerdvm.com/products/claro-florfenicol-terbinafine-mometasone-furoate-otic-solution/
- European Medicines Agency (online) Categorisation of Antibiotics for Use in Animals for Prudent and Responsible Use. Website: www.ema.europa.eu (pdf download).