bovis - Articles
Framycetin
Synonym(s): Neomycin B
Introduction
In the UK, Framycetin is classified as category C (Caution) by the European Medicines Agency (EMA).
Name
- Framycetin sulfate.
Class of drug
- Broad spectrum aminoglycoside antibiotic.
- The World Health Organization (WHO) Critically Important Antimicrobials for Human Medicine; Critically Important – Highest Priority,
Description
Chemical name
- (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol;sulfuric acid.
Molecular formula
- C23H48N6O17S.
Molecular weight
- 712.7.
Physical properties
- White solid.
Storage requirements
- In a closed container <25°C/77°F.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed Papers
- Recent references from PubMed and VetMedResource.
Other sources of information
- Ramsey I (2020) BSAVA Small Animal Formulary. 10th edn. BSAVA, UK.
- World Organization for Animal Health (2021) List of Antimicrobial Agents of Veterinary Importance. Website: www.woah.org.
- Veterinary Medicines Directorate (2018) Summary of Product Characteristics - Ubrostar Red 100 mg / 280 mg / 100 mg, Intramammary Suspension for cattle. Website: www.vmd.defra.gov.uk (pdf download).
- Veterinary Medicines Directorate (2016) Summary of Product Characteristics - Framomycin 150 mg/ml Solution for Injection. Website: www.vmd.defra.gov.uk (pdf download).
- European Medicines Agency (online) Categorisation of Antibiotics for Use in Animals for Prudent and Responsible Use. Website: www.ema.europa.eu (pdf download).
Organisation(s)
- National Office of Animal Health (NOAH) Website: www.noahcompendium.co.uk.
- US Food & Drug Administration (FDA) Website: www.fda.gov.
- Veterinary Medicines Directorate (VMD) Website: www.vmd.defra.gov.uk.