bovis - Articles
Doxycycline
Introduction
In the UK, Doxycycline is classified as category D (Prudence) by the European Medicines Agency (EMA).
Name
- Doxycycline.
Class of drug
- Lipid-soluble tetracycline antibiotic.
Description
Chemical name
- (4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide.
Molecular formula
- C22H24N2O8.
Molecular weight
- 444.4 g/mol.
Physical properties
- Yellow crystalline powder.
Storage requirements
- Store in dry cool place.
- Avoid direct sunlight.
- Store at room temperature, under 30°C/86°F.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
Other sources of information
- Meredith A (2015) Ed. Small Animal Formulary. Part B: Exotic Pets. 9th edn. BSAVA, UK. pp 195.
- Johnson-Delaney C (2010) Guinea Pigs, Chinchillas, Degus and Duprasi. In: BSAVA Manual of Exotic Pets. 5th edn. Eds: Meredith A & Johnson-Delaney C. BSAVA, UK. pp 28–62.
- Bishop Y (2005) The Veterinary Formulary. 6th edn. British Veterinary Association and Royal Pharmaceutical Society, UK.
- Quesenberry K E & Carpenter J W (2004) Formulary. In: Ferrets, Rabbits and Rodents: Clinical Medicine and Surgery. 2nd edn. pp 436-444.
- European Agency for the Evaluation of Medicinal Products (1997) Committee for Veterinary Medicinal Products. Doxycycline. Summary Report (2). Website: www.ema.europa.eu (pdf download).
- Pubchem Doxycycline. NIH U.S. National Library of Medicine. National Center of biotechnology Information.
- VMD (online) Suspected Adverse Reaction Surveillance Scheme (SARSS). Available at: www.vmd.defra.gov.uk.
- NOAH (online) Adverse Reactions Reporting Forms. Available at: www.noahcompendium.co.uk.
- VMD (online) Animal Adverse Reaction Reporting. Available at: www.vmd.defra.gov.uk.
- FDA (online) FDA Adverse Event Reporting System (FAERS). Available at: www.fda.gov.
- European Medicines Agency (online) Categorisation of Antibiotics for Use in Animals for Prudent and Responsible Use. Website: www.ema.europa.eu (pdf download).
Organisation(s)
- National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.