bovis - Articles
Cefapirin
Synonym(s): Cephapirin
Introduction
Name
- Cefapirin (synonym cephapirin).
Class of drug
- First generation semi-synthetic cephalosporin antibiotic.
- Broad-spectrum antibiotic.
- EMA Category C antibiotic (use with caution) Antibiotic selection for UK/European farms.
- The World Health Organization (WHO) has designated first-generation cephalosporins as a Highly Important antimicrobials for human medicine.
Description
- Supportive care.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed Papers
- Recent references from PubMed and VetMedResource.
- Schukken Y H, Zurakowski M J, Rauch B J et al (2013) Non-inferiority trial comparing a first-generation cephalosporin with a third-generation cephalosporin in the treatment of non-severe clinical mastitis in dairy cows. J Dairy Sci 96 (10), 6763-6774 PubMed.
Other sources of information
- Intervet Ireland Ltd (2022) CepraShort 300 mg Intramammary Suspension Summary of Product Characteristics. Health Products Regulatory Authority, UK. Website: www.hpra.ie (pdf download).
- Bimeda Animal Health Ltd (2022) Bimacure 500 mg Intrauterine Suspension for Cattle Summary of Product characteristics. Veterinary Medicines Directorate, UK. Website: www.vmd.defra.gov.uk (pdf download).
- Boehringer Ingelheim, USA (2015) ToDAY® (Cephapirin sodium). Safety Data Sheet. Website: www.bi-vetmedica.com (pdf download).
Organisation(s)
- World Health Organization (2018) Critically Important Antimicrobials for Human Medicine. 6th Revision. Website: https://apps.who.int (pdf download).
- European Medicines Agency (2001) Committee for Veterinary Medicinal Products – Cefapirin Summary Report (2). Website: www.ema.europa.eu (pdf download).
- Compendium of Data Sheets for Animal Medicines (online) Mastiplan® LC, 300 mg/20 mg (Cefapirin/Prednisolone) Intramammary Suspension for Lactating Cows. National Office of Animal Health, UK. Website: www.noahcompendium.co.uk.
- US Food and Drug Administration (online) FDA - Approved Drugs. Website: www.accessdata.fda.gov.