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Ivermectin
Synonym(s): Avermectin, endectocide, macrocyclic lactone.
Introduction
Name
- Ivermectin.
Class of drug
- Avermectin, endectocide, macrocyclic lactone.
Description
Chemical name
- Ivermectin is a mixture of
ivermectin
component H2B1a (5-O-demethyl-22,23-dihydroavermectin A1a; C48H74O14 = 875.1) andivermectin
component H2B1b (5-O-demethyl-25-de(1-methylpropyl)-25-(1-methylethyl)-22,23-dihydroavermectin A1a; C47H72O14 = 861.1).
Physical properties
- Ivermectin is presented as a powder and is made up to a sterile non-aqueous solution.
- The formulations for cattle include: pour-on solutions and solution for injection.
- Formulations are usually yellow or blue aqueous solutions.
Storage requirements
- <25°C.
- Protect from direct light.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed Papers
- Recent references from PubMed and VetMedResource.
Other sources of information
- Yolande Bishop (2005) The Veterinary Formulary. 5th edn. Published in association with the British Veterinary Association.
- National Office of Animal Health (NOAH) Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.