bovis - Articles
Doramectin
Introduction
Name
- Doramectin.
Class of drug
- A semisynthetic member of the avermectin class, structurally similar to abamectin and ivermectin Ivermectin.
- An ecto- and endoparasiticide.
Description
Chemical name
- 25-cyclohexyl-5-O-demethyl-25-de(l-methylpropyl)avermectin A1a.
Molecular formula
- C50H74O14.
Molecular weight
- 899.1 g/mol.
Physical properties
- Solution licensed for injection for cattle and sheep is clear, colorless, to pale yellow oily solution for parenteral administration.
- Pour-on (dermal) solution may be a pale blue color (varies between products).
Storage requirements
- Do not store above 30°C/86°F.
- Do not freeze.
- Do not refrigerate.
- Protect from direct sunlight.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed Papers
- Recent reference from PubMed and VetMedResource.
- Pivoto F L, Cezar A S, Vogel F S F & Leal M L R (2020) Effects of long-term indiscriminate use of macrocyclic lactones in cattle: Parasite resistance, clinical helminthosis, and production losses. Vet Parasitol 20 SciDirect.
- Baez et al (2019) Anthelmintic effect of ivermectin and doramectin on weaned cattle from southern Paraguay. Revista Veterinaria 30 (2), 59-63 VetMedResource.
Other sources of information
- National Office of Animal Health (online) Dectomax 10 mg/ml Solution for Injection. Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.
- National Office of Animal Health (online) Taurador 5 mg/ml Pour-on Solution for Cattle. Compendium of Data Sheets for Animal Medicines. Website: www.noahcompendium.co.uk.
- PubChem (online) Compound Summary Doramectin. National Center for Biotechnology Information. Website: pubchem.ncbi.nlm.nih.gov.