Closantel
Synonym(s): Closantel sodium dihydrate, Anthelmintic
Introduction
Name
- Closantel.
- Usually available as Closantel sodium dihydrate.
Class of drug
- Anthelmintic.
- Endectocide.
- Flukicide.
- Salicylanilides.
Description
Chemical name
- N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)-2-hydroxy-3,5-diiodobenzamide.
Molecular formula
- C22H14Cl2I2N2O2.
Molecular weight
- 663.074 Da.
Physical properties
- Solution for injection, pour on and oral solution.
Storage requirements
- <25°C.
- Protect from light.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed papers
- Recent references from PubMed and VetMedResource.
- Swan G E (1999) The pharmacology of halogenated salicylanilides and their anthelmintic use in animals. J S Afr Vet Assoc 70 (2), 61-70 PubMed.
Other sources of information
- NOAH & VMD (2020) Joint Statement from the National Office of Animal Health (NOAH) and the Veterinary Medicines Directorate (VMD) on the Use of Flukicides in Dairy Cattle. Website: www.noah.co.uk (pdf download).
- Norbrook (online) Closamectin Injection. In: Closamectin solution for injection for cattle and sheep. Website: www.norbrook.com.
- Norbrook (online) Closamectin Pour-On. Website: www.noorbrook.com.
- PubChem (online) Closantel. In: National Library of Medicine, National Centre for Biotechnology Information. Website: https://pubchem.ncbi.nlm.nih.gov.
- Parasitipedia (online) Closantel: Safety Summary for Veterinary Use. Website: https://parasitipedia.net.
- Veterinary Medicines Directorate (online) Product Database. Website: www.vmd.defra.gov.uk.