bovis - Articles
Botulism antitoxin
Synonym(s): Botulism antiserum
Introduction
Name
- Botulism antitoxin.
Class of drug
- Immunologic preparation.
- Botulism antitoxin (equine) heptavalent contains purified F(ab′)2 and F(ab′)2-related immune globulin fragments prepared from equine plasma and has antitoxin activity against botulinum neurotoxins A, B, C, D, E, F, and G.
Description
Physical properties
- Usually provided in single use vials.
- Each single-use vial of Botulism Antitoxin (Equine) (regardless of vial size or fill volume) contains at least 4500, 3300, 3000, 600, 5100, 3000, and 600 units of serotype A, B, C, D, E, F, and G antitoxin, respectively.
Storage requirements
- May be delivered as a frozen product or thawed.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed Papers
- Recent references from PubMed and VetMedResource.
- Braun U (2006) Botulism in cattle. Schweiz Arch Tierheilkd 148 (7), 331-339 PubMed.
Other sources of information
- Drugs.com (2019) Botulism Antitoxin (Equine). Website: www.drugs.com
- The Center for Food Security and Public Health (2018) Botulism. Iowa State University of Science and Technology, USA. Website: www.cfsph.iastate.edu (pdf download).
- Knottenbelt D K & Malalana F (2014) Formulary of Equine Medicine. 2nd edn. Liverpool University Press, UK. ISBN: 0-85323-740-9.
- Bishop Y (2004) The Veterinary Formulary. 6th edn. British Veterinary Association and Royal Pharmaceutical Society, UK.
- FDA (online) FDA Adverse Event Reporting System (FAERS). Available at: www.fda.gov.
- NOAH (online) Adverse Reactions Reporting Forms. Available at: www.noahcompendium.co.uk.
- VMD (online) Animal Adverse Reaction Reporting. Available at: www.vmd.defra.gov.uk.
- VMD (online) Suspected Adverse Reaction Surveillance Scheme (SARSS). Available at: www.vmd.defra.gov.uk.