Detomidine hydrochloride
Introduction
Name
- Detomidine hydrochloride.
Class of drug
- Alpha-2 adrenoceptor stimulant.
Description
Chemical name
- 4-(2,3-Dimethylbenzyl)imidazole hydrochloride.
Molecular formula
- C12H14N2,HCl.
Molecular weight
- 222.7.
Physical properties
- Available as solution for injection
Storage requirements
- Store at room temperature. Protect from light.
Uses
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Administration
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Pharmacokinetics
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Precautions
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Withdrawal Periods
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Adverse Reactions
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Further Reading
Publications
Refereed Papers
- Recent references from PubMed and VetMedResource.
- Alexander D (2014) The bovine caesarean - part two, difficult caesareans (potential pitfalls and how to overcome them). In Practice (36), 15–26.
- Hokkanen A H, Raekallio M R, Salla K, Viitasaari E, Norring M & Vainio O M (2014) Sublingual administration of detomidine to calves prior to disbudding: A comparison with the intravenous route. Vet Anaesth Analg 41 (4), 372–377 PubMed.
- Abrahamsen E J (2013) Chemical restraint and injectable anesthesia of ruminants. Vet Clin North Am Food Anim Pract 29 (1), 209–27 PubMed.
- Alexander D (2013) Bovine caesarean section 1. On-farm operations. In Practice, 35 (10), 574–588 VetMedResource.
- Hallowell G, Potter T & Aldridge B (2012) Medical support for cattle and small ruminant surgical patients. In Practice 34 (4), 226–233 VetMedResource.
- Lin H C & Riddell M G (2003) Preliminary study of the effects of xylazine or detomidine with or without butorphanol for standing sedation in dairy cattle. Vet Therapeu Res Appl Vet Med 4 (3), 285–291 VetMedResource.
- Jedruch J & Gajewski Z (1986) The effect of detomidine hydrochloride (Domosedan) on the electrical activity of the uterus in cows. Acta Veterinaria Scandinavica. Supplementum 82, 189–192 PubMed.
Other sources of information
- Plumb's Veterinary Drugs.
- VMD Product Database.